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CLINICAL INFORMATION for Castor bean

Clinical History

Number of Studies:
1-5
Number of Patients:
1-5
Symptoms:
Urticaria, drowsiness, dyspneic and Quincke's edema (swelling of lips, glottis) after chewing a single bean. Blood pressure was 6 mmHg (Navarro-Rouimi & Charpin 1999 [812]). Note that ingested ricin may prove fatal in a dose of 0.03 gm.

Skin Prick Test

Number of Studies:
0
Food/Type of allergen:
Protocol:
(controls, definition of positive etc)
Number of Patients:
Summary of Results:

IgE assay (by RAST, CAP etc)

Number of Studies:
1-5
Food/Type of allergen:
Not specified
IgE protocol:
CAP-RAST
Number of Patients:
1
Summary of Results:
IgE to castor bean was 80-100 lU/l; i.e., class 5 in the patient of Navarro-Rouimi & Charpin (1999) [812]

Immunoblotting

Immunoblotting separation:

Immunoblotting detection method:
Immunoblotting results:
Not reported

Oral provocation

Number of Studies:
0
Food used and oral provocation vehicle
Blind?
Number of Patients?
Dose response
Symptoms

IgE cross-reactivity and Polysensitisation

Cross reactivity between green coffee and castor bean aeroallergens among coffee workers has been reported.

Other Clinical information

Castor beans are not used for human consumption. The castor plant and its parts are a source of potent inhalant allergens. Navarro-Rouimi & Charpin (1999) [812] conclude that sensitization was by inhalation before chewing the castor bean.

Cross reactivity between green coffee and castor bean aeroallergens among coffee workers has been reported. There are also reports of contact allergy.

There is an intriguing paper which shows that residual allergenic material from castor bean can be identified in the flesh of fish fed a castor bean pomace (detoxified castor bean residue after oil extraction) (Layton 1977 [811])


Reviews (0)

References (2)

Layton LL
Castorbean allergens in tissues of catfish reared on a diet containing castorbean pomace. J Sci Food Agric 28, 399-404 1977
PUBMED ID: 406483
[811]
Navarro-Rouimi R, Charpin D.
Anaphylactic reaction to castor bean seeds. Allergy 54(10):1117 1999
PUBMED ID: 10536895
[812]
This record was last modified on 18-Oct-2006
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